1 / 1
|
DeCS
|
|
|
Descriptor English:
|
|
1-Alkyl-2-acetylglycerophosphocholine Esterase
|
Descriptor Spanish:
|
|
1-Alquil-2-acetilglicerofosfocolina Esterasa
|
Descriptor Portuguese:
|
|
1-Alquil-2-acetilglicerofosfocolina Esterase
|
Synonyms English:
|
|
PAF Acetylhydrolase
Platelet-Activating Factor Hydrolase
|
Tree Number:
|
|
D08.811.277.352.100.680.750.937.249
|
Definition English:
|
|
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA. |
Indexing Annotation English:
|
|
/antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
|
History Note English:
|
|
2004(1983)
|
Allowable Qualifiers English:
|
|
|
Record Number:
|
|
38141
|
Unique Identifier:
|
|
D043203
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS CID-10 SciELO LILACS LIS
|